Susceptibility status of Cx. vishnui subgroup of mosquitoes against different Insecticides and detection of novel mutations in esterase beta gene in Cx. tritaeniorhynchus

Japanese encephalitis (JE) is a mosquito-borne viral disease and several species of the Culex genera can transmit JE. The present study was conducted to observe resistance in Cx. vishnui subgroup against organophosphates, widely used fogging controlling 12 localities Dibrugarh Tinsukia districts Assam, endemic for Susceptibility tests performed revealed both pseudovishnui tritaeniorhynchus were found resistant Organophosphates Malathion (5%) Fenitrothion (1%). Molecular characterization genes responsible depicted two non-synonymous polymorphisms primary JE vector tritaeniorhynchus. To best our knowledge, this first report on detection SNP’s esterase beta (estβ) gene India As data regarding vectors lacking from country, will aid understanding characteristics involved manifestation.